The scientific world was stirred in April by a tantalizing possibility: evidence of life on a distant planet. Using NASA’s James Webb Space Telescope, researchers led by University of Cambridge astrophysicist Nikku Madhusudhan reported detecting dimethyl sulfide (DMS) and dimethyl disulfide (DMDS) — molecules that on Earth are typically produced by microbial life — in the atmosphere of exoplanet K2-18b.
Located 124 light-years away in the habitable zone of a cool dwarf star, K2-18b is believed to be a “Hycean world” — a type of exoplanet that could host liquid water beneath a hydrogen-rich atmosphere. The discovery sparked excitement about the potential for extraterrestrial biology.
But just weeks later, that excitement is facing sharp scrutiny. Independent teams of astronomers from institutions like Arizona State University, the University of Chicago, and the University of Maryland have reanalyzed the data and modeling methods — and they’re not convinced.
“Noisy” Data, Contested Models
Dr. Rafael Luque and Michael Zhang, postdoctoral researchers at the University of Chicago, reviewed the Webb telescope’s near-infrared data and found it to be “noisy” and inconclusive. They argue that the features initially attributed to DMS and DMDS might instead be due to more common molecules like ethane — which, unlike DMS, is not a sign of life.
Adding to the debate, their analysis showed a much higher estimated temperature for the planet — about 422 Kelvin (149°C) — compared to previous estimates. That raises serious doubts about whether the planet could support life as we know it.
Arizona State’s Dr. Luis Welbanks and his team, including Dr. Matt Nixon of the University of Maryland, dug even deeper. They questioned the statistical modeling used by Madhusudhan’s team, arguing that the original framework was too narrow — only allowing one molecule at a time to explain the observed data.
Once their model included a wider array of possible chemical species — 650 in total — the evidence for DMS and DMDS “disappeared,” they said.
A Heated But Healthy Debate
Madhusudhan has welcomed the criticism, saying it contributes to the broader search for truth. He agrees that the current evidence for DMS is only “moderate” — falling short of the five-sigma threshold that scientists typically require to claim a major discovery.
In response to the critiques, the Cambridge team has published a follow-up study using a wider molecular analysis. While they still see DMS as a “promising candidate,” they admit more data and verification are needed.
Welbanks, however, feels the new paper backpedals without fully addressing the original flaws. “The statistical significance claimed in earlier work was the product of arbitrary modeling decisions,” he said.
The Road Ahead
Despite the conflicting results, all parties agree on one thing: the search for life on K2-18b — and beyond — is far from over. The debate underscores the high bar required in astrobiology, where a single molecule can ignite hope or crumble under scrutiny.
“It’s not a failure,” said Welbanks. “We’re testing bold ideas. That’s what science is about.”
As telescopes grow more powerful and models more refined, astronomers believe the first definitive biosignature could arrive within our lifetime. Until then, K2-18b remains not a cradle of life, but a crucible for discovery.

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